个人简介
老五白菜网教授,博士生导师。湖北省仪器仪表协会常务理事,湖北省化学化工学会理事,中国抗癌协会纳米肿瘤学专业委员会委员会委员,中国生物材料学会纳米生物材料分会委员,中国生物医学工程学会纳米医学与工程分会委员,医学检验工程分会委员。2006年获教育部高等学校自然科学一等奖(第二完成人),2017年获湖北省自然科学一等奖(第三完成人),2010年入选教育部“新世纪优秀人才支持计划”,2013年获湖北省青年科技奖,2014年入选武汉市“3551”光谷人才计划。主要从事纳米生物医学传感、微流控芯片及生物电化学等方面的研究工作。主要研究兴趣包括磁控微流控芯片用于疾病标志物检测及肿瘤细胞分选,基于微流控芯片(器官芯片)的病毒与宿主细胞相互作用研究,液滴微流控用于纳米材料合成及单颗粒数字化分析,超灵敏电化学传感用于病原体检测。国家基金委“新型生物医学探针技术基础及应用”创新研究群体及教育部“化学生物学应用基础研究”创新团队骨干成员。主持6项国家自然科学基金、1项国家863重大项目子课题以及1项863专题课题,参加多项973项目及国家重大科学研究计划项目。已在Angew Chem. Int. Ed.,Anal. Chem.,Biomaterials,Lab Chip,Biosens. Bioelectron.等国际杂志上发表SCI学术论文200余篇。
教育经历
1993.09-1997.06 吉林大学化学系 大学本科
1997.09-2002.11 老五白菜网 硕博连读
工作经历
2001.07-2005.11 老五白菜网 讲师
2003.10-2004.10 法国巴黎高等师范学校 博士后
2005.12-2008.11 老五白菜网 副教授
2008.12-至今 老五白菜网 教授
研究方向
磁控微流控芯片用于疾病标志物检测、高灵敏电化学传感
代表成果
1. Bai Yi-Yan; Feng Zhi-Tao; Yang Yu-Jun; Yang Xiao-Yan; Zhang Zhi-Ling*, Current Lifetime of Single-Nanoparticle Collision for Sizing Nanoparticles, Analytical Chemistry, 2022, 94(2):1302-1307.
2. Yang Xiao-Yan; Bai Yi-Yan; Huangfu Yue-Yue; Guo Wen-Jing; Yang Yan-Ju; Pang Dai-Wen; Zhang Zhi-Ling*, Ultrasensitive Electrochemiluminescence Biosensor Based on Closed Bipolar Electrode for Alkaline Phosphatase Detection in Single Liver Cancer Cell, Analytical Chemistry, 2021, 93(3):1757-1763.
3. Tian Yishen; Xu Chun-Miao; Feng Jiao; Huangfu Yueyue; Wang Kai; Zhang Zhi-Ling*, Personalized Gel-Droplet Monocyte Vaccines for Cancer Immunotherapy, Lab on a Chip, 2021, 21(22):4414-4426.
4. Bai Yi-Yan; Wu Zhen; Xu Chun-Miao; Zhang Li; Feng Jiao; Pang Dai-Wen; Zhang Zhi-Ling*, One-to-Many Single Entity Electrochemistry Biosensing for Ultrasensitive Detection of microRNA, Analytical Chemistry, 2020, 92(1):853-858.
5. Xu Chun-Miao; Tang Man; Feng Jiao; Xia Hou-Fu; Wu Ling-Ling; Pang Dai-Wen; Chen Gang*; Zhang Zhi-Ling*, A liquid biopsy-guided drug release system for cancer theranostics: integrating rapid circulating tumor cell detection and precision tumor therapy, Lab on a Chip, 2020, 20(8):1418-1425.
6. Tang Man; Xia Hou-Fu; Xu Chun-Miao; Feng Jiao; Ren Jian-Gang; Miao Fan; Wu Min; Wu Ling-Ling; Pang Dai-Wen; Chen Gang*; Zhang Zhi-Ling*, Magnetic Chip Based Extracorporeal Circulation: A New Tool for Circulating Tumor Cell in Vivo Detection, Analytical Chemistry, 2019, 91(23):15260-15266.
7. Hong Shao-Li; Xiang Meng-Qi; Tang Man; Pang Dai-Wen; Zhang Zhi-Ling*, Ebola Virus Aptamers: From Highly Efficient Selection to Application on Magnetism-Controlled Chips, Analytical Chemistry, 2019, 91(5):3367-3373.
8. Wang Ji; Wang Cheng; Xu Na; Liu Zheng-Fei*; Pang Dai-Wen; Zhang Zhi-Ling*, A virus-induced kidney disease model based on organ-on-a-chip: Pathogenesis exploration of virus-related renal dysfunctions, Biomaterials, 2019, 219:119367.
9. Liu Cui; Xiao Guangjun*; Yang Mengli; Zou Bo*; Zhang Zhi-Ling*; Pang Dai-Wen, Mechanofluorochromic Carbon Nanodots: Controllable Pressure-Triggered Blue- and Red-Shifted Photoluminescence. Angewandte Chemie Interantional Edition, 2018, 57: 1893-1897.
10. Wu, Z.; Guo, W. J.; Bai, Y. Y.; Zhang, L.; Hu, J.; Pang, D. W.; Zhang, Z. L.*, Digital Single Virus Electrochemical Enzyme-Linked Immunoassay for Ultrasensitive H7N9 Avian Influenza Virus Counting. Anal. Chem. 2018, 90:1683-1690.